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Posts Tagged ‘doxycycline’

Cooper has been prescribed so many medicines and supplements to treat his SLO: tetracycline, niacinimide, fish oil, vitamin E, biotin. Plus, on the advice of some other owners of dogs with SLO, I also give him super vitamin B complex and biotin.

Now, the supplements won’t hurt him. In fact, lots of dog owners give their dogs fish oil for their omega-3 fatty acids, which are excellent for a dog’s coat. Though at 6 capsules per day, Cooper gets quite a bit of fish oil.

But the tetracycline — he’s been getting a 500 mg capsule of tetracycline, 3 times per day, for almost 3 years. That’s a lot. A lot.

And it hasn’t been trouble-free. It’s really inconvenient to space out 3 doses of tetracycline so that it’s given as close to every 8 hours as possible. Sometimes it makes him nauseated. And because calcium interferes with the body’s ability to absorb tetracycline, Cooper can’t get food with calcium in it within 2 hours either side of taking the tetracycline. At his dosing schedule, that means almost no dairy — no cheese, which he likes, and no yogurt, which he also likes and which would also help restore the healthy bacteria in his gut that the tetracycline kills.

I’ve been hoping for an alternative, but one that would not lead to a worsening of his SLO. Some inconvenience, a little nausea, and no dairy is nothing compared to the pain of SLO.

Fortunately, yesterday my vet has suggested that we switch to doxycycline. It’s a “semisynthetic” version of tetracycline with some definite advantages. It doesn’t bind with calcium like tetracycline, so the vet has given his OK to give Cooper yogurt. And best, of all, its half-life is 18-22 hours compared to tetracycline’s 6-11 hours, which means that he only needs to take it two times per day, instead of tetracycline’s 3 times per day. And if all goes well, we might be able to reduce it down to 1 time per day sometime in the future.

So we started the new regimen today:

  • doxyclycline, 100 mg, 2x/day
  • niacinimide, 500 mg, 3x/day
  • fish oil capsules, 2-1000 mg, 3x/day
  • vitamin E, 400 IU, 2x/day
  • biotin, 2500 mcg, 1x/day
  • vitamin B, super complex, 2x/day
  • Perma-Clear, 1 capsule, 3x/day
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